I have been receiving some wonderful responses from patients with overactive bladder syndrome who have failed several oral treatments for this problem. Standard therapy for this problem includes antimuscarinics with and without the uroselective beta agonist Myrbetrique. When these medications fail, intravesical Botox is a good option.
Intravesical Botox is a safe and minimally invasive procedure which requires light sedation and is done as an outpatient. The procedure is performed via a standard cystoscope, through which multiple submucosal injections of Botox are administered. Most patients begin to notice relief of their voiding symptoms within 24 hours. Generally the procedure wears off in 6 to 9 months, at which time it can be repeated. It is covered by most insurance plans.
Transient urinary retention is the most common complication from this procedure, however, it is not very common. Talk to your doctor about whether this treatment is right for you.